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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 1
1971 4
1972 5
1973 7
1974 4
1975 14
1976 11
1977 19
1978 23
1979 22
1980 16
1981 30
1982 25
1983 40
1984 52
1985 48
1986 62
1987 90
1988 71
1989 65
1990 54
1991 35
1992 30
1993 30
1994 30
1995 29
1996 19
1997 30
1998 22
1999 28
2000 28
2001 36
2002 23
2003 23
2004 22
2005 33
2006 37
2007 30
2008 34
2009 38
2010 41
2011 56
2012 76
2013 84
2014 60
2015 61
2016 78
2017 88
2018 91
2019 103
2020 106
2021 108
2022 101
2023 106
2024 55

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2,260 results

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Page 1
T-2 toxin metabolism and its hepatotoxicity: New insights on the molecular mechanism and detoxification.
Song W, Wang Y, Huang T, Liu Y, Chen F, Chen Y, Jiang Y, Zhang C, Yang X. Song W, et al. Environ Pollut. 2023 Aug 1;330:121784. doi: 10.1016/j.envpol.2023.121784. Epub 2023 May 9. Environ Pollut. 2023. PMID: 37169237 Review.
Liver is the major detoxifying organ which also makes it the main target of T-2 toxin. After being absorbed by intestine, the first pass effect will reduce the level of T-2 toxin in blood indicating that liver is the main metabolic site o …
Liver is the major detoxifying organ which also makes it the main target of T-2 toxin. After being absorbed by intestin …
T-2 Toxin-The Most Toxic Trichothecene Mycotoxin: Metabolism, Toxicity, and Decontamination Strategies.
Janik E, Niemcewicz M, Podogrocki M, Ceremuga M, Stela M, Bijak M. Janik E, et al. Molecules. 2021 Nov 14;26(22):6868. doi: 10.3390/molecules26226868. Molecules. 2021. PMID: 34833960 Free PMC article. Review.
Among trichothecenes, T-2 toxin is the most toxic fungal secondary metabolite produced by different Fusarium species. ...Depending on the age, way of exposure, and dosage, intoxication manifests by vomiting, feed refusal, stomach necrosis, and skin irritation …
Among trichothecenes, T-2 toxin is the most toxic fungal secondary metabolite produced by different Fusarium species. . …
T-2 toxin and its cardiotoxicity: New insights on the molecular mechanisms and therapeutic implications.
Dai C, Das Gupta S, Wang Z, Jiang H, Velkov T, Shen J. Dai C, et al. Food Chem Toxicol. 2022 Sep;167:113262. doi: 10.1016/j.fct.2022.113262. Epub 2022 Jul 2. Food Chem Toxicol. 2022. PMID: 35792220 Review.
T-2 toxin is one of the most toxic and common trichothecene mycotoxins, and can cause various cardiovascular diseases. ...T-2 toxin exposure can cause cardiac fibrosis and finally lead to cardiac dysfunction. ...
T-2 toxin is one of the most toxic and common trichothecene mycotoxins, and can cause various cardiovascular diseases. …
Toxicity and detoxification of T-2 toxin in poultry.
Li SJ, Zhang G, Xue B, Ding Q, Han L, Huang JC, Wu F, Li C, Yang C. Li SJ, et al. Food Chem Toxicol. 2022 Nov;169:113392. doi: 10.1016/j.fct.2022.113392. Epub 2022 Aug 28. Food Chem Toxicol. 2022. PMID: 36044934 Review.
This review summarizes the updated knowledge on the toxicity of T-2 on poultry, followed by potential strategies for detoxification of T-2 in poultry diet. ...BBSH 797 strain), and indirect detoxifying agents (e.g., plant-derived antioxidants). These …
This review summarizes the updated knowledge on the toxicity of T-2 on poultry, followed by potential strategies for detoxific …
Review of the Reproductive Toxicity of T-2 Toxin.
Yang X, Liu P, Cui Y, Xiao B, Liu M, Song M, Huang W, Li Y. Yang X, et al. J Agric Food Chem. 2020 Jan 22;68(3):727-734. doi: 10.1021/acs.jafc.9b07880. Epub 2020 Jan 8. J Agric Food Chem. 2020. PMID: 31895560 Review.
T-2 toxin, an inevitable environmental pollutant, is the most toxic type A trichothecene mycotoxin. Reproductive disruption is a key adverse effect of T-2 toxin. Herein, this paper reviews the reproductive toxicity of T-2 …
T-2 toxin, an inevitable environmental pollutant, is the most toxic type A trichothecene mycotoxin. Reproductive disrup …
Review of neurotoxicity of T-2 toxin.
Wang Y, Wang B, Wang P, Hua Z, Zhang S, Wang X, Yang X, Zhang C. Wang Y, et al. Mycotoxin Res. 2024 Feb;40(1):85-95. doi: 10.1007/s12550-024-00518-5. Epub 2024 Jan 13. Mycotoxin Res. 2024. PMID: 38217761 Review.
Hence, T-2 toxin has become an unavoidable pollutant in food for humans and animals. ...Thus, alleviating oxidative stress has become a potential target for relieving the neurotoxicity induced by T-2 toxin. Future efforts should be devote …
Hence, T-2 toxin has become an unavoidable pollutant in food for humans and animals. ...Thus, alleviating oxidative str …
An update on T-2 toxin and its modified forms: metabolism, immunotoxicity mechanism, and human exposure assessment.
Wu Q, Qin Z, Kuca K, You L, Zhao Y, Liu A, Musilek K, Chrienova Z, Nepovimova E, Oleksak P, Wu W, Wang X. Wu Q, et al. Arch Toxicol. 2020 Nov;94(11):3645-3669. doi: 10.1007/s00204-020-02899-9. Epub 2020 Sep 10. Arch Toxicol. 2020. PMID: 32910237 Review.
Recently, several novel metabolites, including 3',4'-dihydroxy-T-2 toxin and 4',4'-dihydroxy-T-2 toxin, have been uncovered. The enzymes CYP3A4 and carboxylesterase contribute to T-2 toxin metabolism, with 3'-hydroxy- …
Recently, several novel metabolites, including 3',4'-dihydroxy-T-2 toxin and 4',4'-dihydroxy-T-2 toxin …
T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods.
Li Y, Wang Z, Beier RC, Shen J, De Smet D, De Saeger S, Zhang S. Li Y, et al. J Agric Food Chem. 2011 Apr 27;59(8):3441-53. doi: 10.1021/jf200767q. Epub 2011 Mar 25. J Agric Food Chem. 2011. PMID: 21417259 Review.
This review focuses on the toxicity and metabolism of T-2 toxin and analytical methods used for the determination of T-2 toxin. ...This review will contribute to a better understanding of T-2 toxin exposure in animals …
This review focuses on the toxicity and metabolism of T-2 toxin and analytical methods used for the determination of …
T-2 toxin induces cardiotoxicity by activating ferroptosis and inhibiting heme oxygenase-1.
Wang C, He J, Jin H, Xiao H, Peng S, Xie J, Zhang L, Guo J. Wang C, et al. Chemosphere. 2023 Nov;341:140087. doi: 10.1016/j.chemosphere.2023.140087. Epub 2023 Sep 5. Chemosphere. 2023. PMID: 37678596
T-2 toxin is known to be highly toxic to the cardiovascular system, but the precise mechanisms that lead to T-2 toxin-induced cardiotoxicity are not yet fully understood. ...These findings provide novel insights into the mechanism of T …
T-2 toxin is known to be highly toxic to the cardiovascular system, but the precise mechanisms that lead to T- …
T-2 toxin inhibits osteoblastic differentiation and mineralization involving mutual regulation between Wnt signaling pathway and autophagy.
Zhang J, Wang P, Song M, Zhang X, Huo S, Du J, Li B, Cao Z, Li Y. Zhang J, et al. Chem Biol Interact. 2023 Jan 5;369:110266. doi: 10.1016/j.cbi.2022.110266. Epub 2022 Nov 17. Chem Biol Interact. 2023. PMID: 36402210
T-2 toxin can accumulate in bone and cause bone development disorders. Osteoblast is the functional cell responsible for bone formation. Whereas, the mechanism of T-2 toxin toxicity on osteoblast remains unknown. In present study, MC3T3-E …
T-2 toxin can accumulate in bone and cause bone development disorders. Osteoblast is the functional cell responsible fo …
2,260 results